Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China. College of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China. shuhai@xmu.edu.cn. State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China. shuhai@xmu.edu.cn. Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. drliukun@sjtu.edu.cn.